Disseminated Fusarium Infections in Patients Receiving Posaconazole Prophylaxis: A Report of 2 Patients and Brief Review of the Literature
- 1 M.D.Roger Williams Medical Center/Boston University School of Medicine, United States
Abstract
Fusarium is a filamentous fungi that has emerged as a frequent cause of invasive infections in immunocompromised patients. Dermatologists often play a critical role in diagnosing fusariosis, as greater than 70% of patients with disseminated infections have cutaneous involvement, and microbiologic evaluation of skin specimens provides the diagnosis in the majority of cases. Second-generation triazoles are typically the most effective medications in treating invasive Fusarium infections, and we discuss the benefits of using these medications, as well as detail the side effects of these therapeutic agents.
DOI: https://doi.org/10.3844/ajidsp.2015.113.116
Copyright: © 2015 John Byrne Fournier, Vinod Thomas, Catherine Breen, Jonathan Cannella, Douglas Heiner, Todd Roberts and Gail Skowron. This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Fusarium
- Invasive Fungal Infection
- Posaconazole
- Voriconazole